Dr Alec Redwood
PhD

Associate Professor in Immunology

Publications

Journals

  • Pavlos, R., McKinnon, E., Ostrov, D., Peters, B., Buus, S., Koelle, D., Chopra, A., Schutte, R., Rive, C., Redwood, A., Restrepo, S., Bracey, A., Kaever, T., Myers, P., Speers, E., Malaker, S., Shabanowitz, J., Jing, Y., Gaudieri, S., Hunt, D., Carrington, M., Haas, D., Mallal, S., Phillips, E., (2017), Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles, Scientific Reports, 7, 1, .
  • Morabito, K., Ruckwardt, T., Redwood, A., Moin, S., Price, D., Graham, B., (2017), Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung, Mucosal Immunology, 10, 2, pages -.
  • Jing, L., Laing, K., Dong, L., Russell, R., Barlow, R., Haas, J., Ramchandani, M., Johnston, C., Buus, S., Redwood, A., White, K., Mallal, S., Phillips, E., Posavad, C., Wald, A., Koelle, D., (2016), Extensive CD4 and CD8 T Cell Cross-Reactivity between Alphaherpesviruses, Journal of Immunology, 196, 5, pages 2205 - 2218.
  • Murphy, A., Redwood, A., Jarvis, M., (2016), Self-disseminating vaccines for emerging infectious diseases, Expert Review of Vaccines, 15, 1, pages 31 - 39.
  • Konvinse, K., White, K., Pavlos, R., Redwood, A., Trubiano, J., Ergen, E., Mallal, S., Phillips, E., (2016), Characterizing immune responses in severe T-cell mediated adverse drug reaction, Journal of Immunology, 196, 191:24, pages -.
  • Gimeno Brias, S., Stack, G., Stacey, M., Redwood, A., Humphreys, I., (2016), The Role of IL-22 in Viral Infections: Paradigms and Paradoxes, Frontiers in Immunology, 7, 211, pages -.
  • McWhorter, A., Smith, L., Shellam, G., Redwood, A., (2015), Murine cytomegalovirus strains co-replicate at multiple tissue sites and establish co-persistence in salivary glands in the absence of Ly49H-mediated competition, Journal of General Virology, 96, 5, pages 1127 - 1137.

Publications prior to Murdoch

Journal articles

  1. Inhibition of the TRAIL death receptor by CMV reveals its importance in NK cell-mediated antiviral defense.  Shilpi Verma, Andrea Loewendorf, Qiao Wang, Alec Redwood & Chris A Benedict. 2014. PLoS Pathogens. 10(8): e1004268.
  2. McWhorter, A. R., Smith L. M., Chan, B., Masters, L. L., Shellam, G. R., Redwood, A. J.  2013. Natural killer cell dependent within-host competition arises during multiple MCMV infection: Consequences for Viral Transmission and Evolution. PLoS Pathogens, 9, e1003111.
  3. Smith L. M., McWhorter, A. R., Shellam, G. R. and Redwood, A. J. 2013. The genome of murine cytomegalovirus is shaped by purifying selection and extensive recombination. Virology,435, 258-268.
  4. Cunningham, P. T., Lloyd, M. L., Harvey, N. L., Williams, E., Hardy, C. M.,Redwood, A. J., Lawson, M. A. and Shellam, G. R. 2011. Promoter control over foreign antigen expression in a murine cytomegalovirus vaccine vector. Vaccine, 29, 141-151.
  5. Pletneva M, Fan H, Park J-J, Radojcic V, Jie C, Yu Y, Chan C, Redwood, A., Pardoll D, Housseau F. 2009. Interferon-producing killer dendritic cells are antigen presenting cells endowed with T cell cross-priming capacity. Cancer Research. 69, 6607-14.
  6. Nikolovski. S., Lloyd. M. L., Harvey, N., Hardy. C. M, Shellam. G. R. and Redwood. A. J. 2009. Overcoming innate host resistance to vaccination: employing a genetically distinct strain of murine cytomegalovirus avoids vector-mediated resistance to virally vectored immunocontraception. Vaccine. 27, 5226-5232
  7. Mans, J., Zhi, L., Revilleza, M. J., Smith, L., Redwood, A., Natarajan, K., and Margulies, D. H. 2009. Structure and Function of Murine Cytomegalovirus MHC-I-like Molecules-how the virus turned the host defense to its advantage. Immunologic Research. 43, 264-279.
  8. Smith, L. M., McWhorter, A.R., Masters, L. L., Shellam, G. R., and Redwood, A. J. 2008. Laboratory strains of murine cytomegalovirus are genetically similar but phenotypically distinct from wild strains of virus. Journal of Virology. 82, 6689-6696
  9. Gorman, S., Lloyd, M. L., Smith, L. E., Lawson, M. A., Redwood, A. J. and Shellam. G. R. 2008. Prior infection with murine cytomegalovirus (MCMV) limits the immunocontraceptive effects of an MCMV vector expressing the mouse zona-pellucida-3 protein. Vaccine. 26, 3860–3869.
  10. Redwood, A. J., Smith, L. M., Lloyd, M. L., Hinds, L. A., Hardy, C. M. and Shellam, G. R. 2007. Prospects for virally vectored immunocontraception in the control of wild house mice (Mus domesticus). Wildlife Research. 34, 1-10.
  11. Redwood, A. J., Harvey, N. L., Lloyd, M. L., Lawson, M. A., Hardy, C. M. and Shellam, G. R. 2007. Viral vectored immunocontraception: screening of multiple fertility antigens using murine cytomegalovirus as a vaccine vector. Vaccine.25, 698-708.
  12. Smith, L. M., Shellam, G. R. and Redwood, A. J. 2006. Genes of murine cytomegalovirus exist as a number of distinct genotypes. Virology. 352, 450-465.
  13. Hardy, C. M, Hinds, L. A, Kerr, P. J, Lloyd, M. L, Redwood, A. J, Shellam, G. R. and Strive, T. 2006. Biological control of vertebrate pests using virally vectored immunocontraception.” Journal of Reproductive Immunology. 71, 102-111.
  14. Redwood, A.J., Messerle, M., Harvey, N.L., Hardy, C. M., Koszinowski, U. H., Lawson, M. A. and Shellam, G. R. 2005. Use of a murine cytomegalovirus, K181-derived, bacterial artificial chromosome as a vaccine vector for immunocontraception. Journal of Virology. 79, 2998-3008.
  15. Smith, L.M., Lloyd, M. L., Harvey, N.L., Redwood, A. J., Lawson, M. A. and Shellam, G. 2005. Species specificity of a murine immunocontraceptive utilizing murine cytomegalovirus as a gene delivery vector. Vaccine. 23, 2959-2969.
  16. Redwood, A. J. and Tennant. M. 2001. Cellular survival in rat vein-to-artery grafts; extensive depletion of donor cells. Cell and Tissue Research. 306, 251-256.
  17. Redwood, A. J., Moore, S., Sayadelmi, L. and. Tennant, M. 1999. Autogenous artery grafts in hypertensive (SHR) rats do not have increased smooth muscle cell hyperplasia in the graft neo-intima, compared with grafts in normotensive rats. Journal of Anatomy. 195, 407-412.

 

 

Book Chapters

  1. Redwood, A. J., Shellam, G. R. and Smith, L. M. 2013. Molecular Evolution of MCMV Genomes. 2nd Edition Cytomegaloviruses; From Molecular Pathogenesis to Intervention. Edited by Mathias Reddehase. Caister Academic Press, Wymondham.
  2. Redwood, A. J., Smith, L. M. and Shellam, G.R 2008. “Murine and non-primate cytomegaloviruses”. In, Encyclopaedia of Virology. Third edition, edited by BWJ Mahy and MHV van Regenmortel, Elsevier. Oxford. 624-634.
  3. Shellam, G. R., Redwood, A. J., Smith, L. M., Gorman, S. 2007. “Murine cytomegaloviruses and other herpesviruses”. In, The Mouse in Biomedical Research, Second Edition, edited by Fox, J. G., Barthold, S. W., Davisson, M. T., Newcomer, C. E., Quimby, F. W., Smith, A. L. Academic Press. Amsterdam. 1-48.
  4. Robinson, W. S., Sellner, L., Redwood, A., Leong, C. C., Davidson, J. A., Peroni, D. J., Marzo, A. L., Garlepp, M. J. and Scott. B. 1996. “New techniques for evaluating lung immunology and immunopathology”. In, Immunopathology of lung disease. Edited by, Krandin, R. L. and Robinson, W.S. Butterworth-Heinemann, Boston. 541-567.

 

Published Abstracts

Lloyd ML, Smith LM, Redwood A, Hardy C, Shellam GR (2010). The use of recombinant vaccines to induce effective contraception in mice. Journal of Reproductive Immunology 86: 35-36.