Dr Anthony Armson
BSc (Hon) RN PhD

Senior Lecturer

About me

I am Senior lecturer in Genetics, Immunology and Microbiology in the School of Health Professions at Murdoch University. Currently I am unit coordinator for CHI205 (Genetics, Immunology and Microbiology), OBRD251 (Wellbeing OUA), CHI509 Public Health and for BRD251 (Wellbeing). I have a science degree with honours and a PhD in biochemistry. Prior to completing my science studies I worked as a registered nurse and I maintain my nursing registration on the Nursing and Midwifery Board of Australia. As a nurse and a scientist I enjoy linking the biochemistry theory to real life examples. In 2008 I won the Vice Chancellors Excellence in Teaching award. I recently moved to the School of Health Professions from The School of Nursing and Midwifery in 2011.
My previous work experience includes working as an RN in a number of hospitals in Sydney and Perth before commencing studies at Murdoch University and Curtin University. I have been at Murdoch since 1996 working as a postdoctoral research fellow before joining the new School of Nursing in 2003 where I was one of 3 founding academic staff. I left this position in early 2011 looking for a change in teaching challenges.

Research:

My research areas of interest are protozoan biochemistry and Ross River virus host/virus interactions. I have published peer reviewed papers and co-edited a book on protozoan parasites with particular focus on Giardia and Cryptosporidium. I have also researched in the area of drug discovery against protozoan parasites including those responsible for malaria and sleeping sickness. I have presented at national and international conferences and have a number of publications, the most significant of which examines the effects of treatment of cryptosporidiosis in infected mice.

Teaching area

I am one of two coordinators of the semester 1 foundation unit Wellbeing FDN111 and I also coordinate this unit in Open Universites Australia (OUA) in teaching period 2 and 4. In semester two I am coordinator of the chiropractic unit Immunology, Genetics and Microbiology CHI305.

Research areas

My research areas include chemotherapeutic targets in parasitic protozoa and neamtodes. I also have an interest in the immunological responses and interactions between host and Ross River virus. This work has been mostly in collaboration with Dr Phil Stumbles. Lastly I am currently exaimining ideal methods for teaching science based units to chiropractic students in collaboration with Associate Professor Bruce Walker, Dr Dominique Losco and Dr Amanda Meyer. This current research area has been through initiating a BEME review.

Awards and grants

Awards

Vice Chancellors Award for Excellence in Teaching 2008.

Grants

  • Chief Investigator on ARC Strategic Partnership with Industry – Research and Training (SPIRT) grant titled “An examination of tubulin binding compounds in protozoa using photoaffinity labelling, antibodies and sequence analysis and mutation.” Funding received $285, 000.00 (1998-2000).
  • Chief investigator on Murdoch University SRG small Research Grant “Binding interactions of dinitroanilines and benzimidazoles with protozoan tubulin.” Funding received $7,000 (2000).
  • Chief investigator on Murdoch University SRG small Research Grant “Drug design and chemotherapy against the trypanosomatids” Funding received $20, 029 (2001)
  • Chief Investigator on ARC Linkage grant “Exploitation of a Novel Drug Target for Controlling Animal Trypanosomiasis.” Total over 3 years $379, 493 (2002-2004)
  • Investigator on Meat and Livestock Australia grant “Aetiology and epidemiology of scouring prime lambs at abattoirs” $94,000 (2002)
  • Chief investigator on WABRI grant “Assessment of Tubulin Binding using BIACore” $25,000 for 1 yr beginning (2003)
  • Chief investigator on ARC linkage grant “Validating protozoa-specific drug targets using peptides from biodiverse gene fragment libraries” $310,000 (2003-2005)

Doctoral and masters supervisions

  • Natalie Giles 2005 PhD
  • Andrew Low 2004 PhD
  • Louisa MacDonald 2003 PhD
  • Nilakshi Jayasakara 2007 Hons
  • Dean Pemberton 2008 Hons
  • Helga Sebastian 2008 Hons
  • Stella Okello 2010 Hons

Publications

Chapters

  • Armson, A., (2003),The application of quantitive-PCR for high-throughput screening of novel compounds against Cryptosporidium parvum in vitro and their subsequent IC50 determination,In: Cryptosporidium: From Molecules to Disease, Elsevier B.V, pages 668 to 673.
  • Armson, A., (2003),An examination of the activity of the dinitroanilines on Cryptosporidium parvum in vitro,In: Cryptosporidium: From Molecules to Disease, Elsevier B.V, pages 661 to 664.
  • Armson, A., Reynoldson, J., Thompson, R., (2003),A Review of Chemotheraputic Approaches to the Treatment of Cryptosporidium,In: Cryptosporidium: From Molecules to Disease, Elsevier B.V, pages 395 to 403.

Journals

  • Losco, C., Grant, W., Armson, A., Meyer, A., Walker, B., (2017), Effective methods of teaching and learning in anatomy as a basic science: A BEME systematic review: BEME guide no. 44, Medical Teacher, 39, 3, pages 234 - 243.
  • Walker, B., Armson, A., Hodgetts, C., Jacques, A., Chin, F., Kow, G., Lee, H., Wong, M., Wright, A., (2017), Knowledge, attitude, influences and use of complementary and alternative medicine (CAM) among Chiropractic and nursing students, Chiropractic & Manual Therapies, 25, 29, pages -.
  • Meyer, A., Stomski, N., Innes, S., Armson, A., (2016), Student performance on practical gross anatomy examinations is not affected by assessment modality, Anatomical Sciences Education, 9, 2, pages 111 - 120.
  • Meyer, A., Stomski, N., Losco, C., Armson, A., (2016), The influence of anatomy app use on chiropractic students' learning outcomes: A randomised controlled trial, Chiropractic & Manual Therapies, 24, 1, pages -.
  • Meyer, A., Stomski, N., Innes, S., Armson, A., (2016), VARK learning preferences and mobile anatomy software application use in pre-clinical chiropractic students, Anatomical Sciences Education, 9, 3, pages 247 - 254.
  • Armson, A., Meyer, A., Losco, B., Motavallizadeh Ardakani, E., Walker, B., (2016), Immunology knowledge as one of the basic sciences that forms the foundations to developing sound clinicians, The Journal of Chiropractic Education: promoting excellence in chiropractic education, 30, 2, pages 108 - 113.
  • Meyer, A., Armson, A., Losco, C., Losco, B., Walker, B., (2015), Factors influencing student performance on the carpal bone test as a preliminary evaluation of anatomical knowledge retention, Anatomical Sciences Education, 8, 2, pages 133 - 139.
  • Jefferies, R., Yang, R., Milech, N., Estcourt, A., Armstrong, T., Hopkins, R., Watt, P., Reid, S., Armson, A., Ryan, U., (2015), Target validation of the inosine monophosphate dehydrogenase (IMPDH) gene in Cryptosporidium using Phylomer peptides, Experimental Parasitology, 148, , pages 40 - 48.
  • Walker, B., Losco, C., Armson, A., Meyer, A., Stomski, N., (2014), The association between pain diagram area, fear-avoidance beliefs, and pain catastrophising, Chiropractic and Manual Therapies (formerly Chiropractic and Osteopathy), 22, 5, pages 1 - 5.
  • Giles, N., Armson, A., Reid, S., (2009), Characterization of trifluralin binding with recombinant tubulin from Trypanosoma brucei, Parasitology Research, 104, 4, pages 893 - 903.
  • Armson, A., Yang, R., Thompson, J., Johnson, J., Reid, S., Ryan, U., (2009), Giardia genotypes in pigs in Western Australia: Prevalence and association with diarrhea, Experimental Parasitology, 121, 4, pages 381 - 383.
  • Yang, R., Power, M., Hufschmid, J., Beveridge, I., Reid, S., Ng, J., Ryan, U., Armson, A., (2008), Identification of zoonotic Giardia genotypes in marsupials in Australia., Experimental Parasitology, 120, , pages 88 - 93.
  • Jefferies, R., Watt, P., Hopkins, R., Sotzik, F., Reid, S., Armson, A., Boxell, A., Ryan, U., (2008), In vitro analysis of the TAT protein transduction domain as a drug delivery vehicle in protozoan parasites, Experimental Parasitology, 118, 3, pages 303 - 307.
  • Boxell, A., Jefferies, R., Watt, P., Hopkins, R., Sotzik, F., Reid, S., Armson, A., Ryan, U., (2008), Pyrrhocoricin as a potential drug delivery vehicle for Cryptosporidium parvum, Experimental Parasitology, 119, 2, pages 301 - 303.
  • Johnson, J., Samarasinghe, B., Buddle, R., Armson, A., Ryan, U., (2008), Molecular Identification and Prevalence of Isospera sp. in pigs in Western Australia using PCR-RFLP assay, Experimental Parasitology, 120, 2, pages 191 - 193.
  • Ng, J., Eastwood, K., Durrheim, D., Massey, P., Walker, B., Armson, A., Ryan, U., (2008), Evidence supporting zoonotic transmission of Cryptosporidium in rural New South Wales., Experimental Parasitology, 119, , pages 192 - 195.
  • Johnson, J., Reid, S., Buddle, J., Armson, A., Ryan, U., (2008), Prevalence of Cryptosporidium genotypes in pre and post-weaned pigs in Australia, Experimental Parasitology, 119, , pages 418 - 421.
  • MacDonald, L., Armson, A., Thompson, R., Reynoldson, J., (2004), Characterisation of benzimidazole binding with recombinant tubulin from Giardia duodenalis, Encephalitozoon intestinalis, and Cryptosporidium parvum, Molecular and Biochemical Parasitology, 138, , pages 89 - 96.
  • Armson, A., Thompson, R., Reynoldson, J., (2003), A review of chemotherapeutic approaches to the treatment of Cryptosporidiosis, Expert Review of Anti-infective Therapy, 1, , pages 297 - 350.
  • MacDonald, L., Armson, A., Thompson, R., Reynoldson, J., (2003), Characterization of factors favoring the expression of soluble protozoan tubulin proteins in Escherichia coli, Protein Expression and Purification, 29, , pages 117 - 122.
  • Dow, G., Armson, A., Boddy, M., Itenge, T., McCarthy, D., Parkin, J., Thompson, R., Reynoldson, J., (2002), Plasmodium: assessment of the antimalarial potential of trifluralin and related compounds using a rat model of Malaria, Rattus norvegicus, Experimental Parasitology, 100, , pages 155 - 160.
  • MacDonald, L., Sargent, K., Armson, A., Thompson, R., Reynoldson, J., (2002), The development of a real-time quantitative-PCR method for characterisation of a Cryptosporidium parvum in vitro culturing system and assessment of drug efficacy, Molecular and Biochemical Parasitology, 121, , pages 279 - 282.
  • Armson, A., Menon, K., O'Hara, A., MacDonald, L., Read, C., Sargent, K., Thompson, R., Reynoldson, J., (2002), Efficacy of oryzalin and associated histological changes in Cryptosporidium-infected neonatal rats, Parasitology (Cambridge), 125, , pages 113 - 117.
  • Armson, A., (2001), Expression of Giadia duodenalis b-tubulin as a soluble protein in Escherichia coli, Protein Expression and Purification, 22, , pages 25 - 30.
  • MacDonald, L., Armson, A., Thompson, R., Reynoldson, J., (2001), Expression of Giardia duodenalis B-Tubulin as a Soluble Protein in Escherichia coli, Protein Expression and Purification, 22, , pages 25 - 30.
  • Ryan, U., Buddle, J., Armson, A., Elliot, A., Thompson, R., (2000), Molecular and biological characterisation of Cryptosporidium in pigs, Australian Veterinary Journal, 77, , pages 44 - 47.
  • Armson, A., Kamau, S., Grimm, F., Reynoldson, J., Best, W., MacDonald, L., Thompson, R., (1999), A comparison of the effects of a benzimidazole and the dinitroanilines against Leishmania infantum, Acta Tropica, 73, , pages 303 - 311.
  • Armson, A., Meloni, B., Reynoldson, J., Thompson, R., (1999), Assessment of drugs against Cryptosporidium parvum using a simple in vitro screening method, FEMS Microbiology Letters, 178, , pages 227 - 233.
  • Armson, A., (1999), A comparison of the leishmaniacidal effects of the benzimidazoles and the dinitroanilines, Acta Tropica, 73, , pages 303 - 311.
  • Armson, A., (1999), A Comparison of the in vitro and in vivo effects of two dinitroanilines against Cryptosporidium parvum in neonatal mice., FEMS Immunology and Medical Microbiology, 26, , pages 109 - 113.

 

Invited Reviews

  • Armson, A, Reynoldson, JA and Thompson, RCA. (2003). A Review of Chemotherapeutic approaches to the treatment of cryptrosporidiosis. Expert Review of Anti-infective Agents. 2: 297-305.

Books

  • Thompson, RCA, Armson, A and Ryan (eds) Cryptosporidium From Molecules to Disease. 2003 Elsevier, Sydney

Published abstracts

  • Armson. A, Thompson. R.C.A, Grubb. W.B., Mendis. A.H.W. (1992) “Steady-state contents of glycolytic, tricarboxylic acid cycle (TCA) intermadiates and adenylate nucleotides pools in Strongyloides ratti infective (L3) larvae.” Proceedings of the Australian/New Zealand Societies fo Parasitology, Auckland September 1992 (suppl).
  • Dawson. S, Armson. A, Reynoldson. J.A, Thompson. R.C.A, and Mendis. A.H.W. (1992) “Glycogen phosphorylase (E.C.2.4.1.1.) and phosphoglucomutase activities in Giardia duodenalis trophozoites.” Proceedings of the Australian/New Zealand Societies for Parasitology, Auckland September 1992 (suppl).
  • Armson. A, Thompson. R.C.A, Grubb. W.B., Mendis. A.H.W. (1992) “Strongyloides ratti: Fumerate reductase (FR) and succinate dehydrogenase (SDH) activities of infective (L3) larvae.” Proceedings of the Australian/New Zealand Societies fo Parasitology, Auckland September 1992 (suppl).
  • Armson. A, Reynoldson. J.A, Thompson. R.C.A, Fuhrman. J.A, Grubb. W.B, and Mendis A.H.W. (1992) “The effects of Albendazole and Diflubenzuron on Strongyloides ratti in Sprague Dawley rats.” Proceedings of the Australian/New Zealand Societies for Parasitology, Auckland September 1992 (suppl).
  • Armson. A, Thompson. R.C.A, Grubb. W.B., Mendis. A.H.W. (1992) “Do infective larvae of Strongyloides ratti possess a fumerate reductase (FR) like most other parasites? Is FR sensitive to thiabendazole?” Proceedings of the First Annual Scientific Meeting of the Fremantle Tropical Medicine Group. (December 1992), page 19-20
  • Armson. A, and Mendis. A.H.W. (1992) “The effects of two electron transport (ET) inhibitors (720C80 and 993C76) on murine strongyloidiasis: a comparison with albendazole (ABZ).” Proceedings of the First Annual Scientific Meeting of the Fremantle Tropical Medicine Group. (December 1992), page 11-12
  • Armson. A, Thompson. R.C.A, Grubb. W.B., Mendis. A.H.W. (1992) “What enzymes regulate glucose metabolism in the infective (L3) larvae of Strongyloides ratti? What is the energy status of L3 larvae?” Proceedings of the First Annual Scientific Meeting of the Fremantle Tropical Medicine Group. (December 1992), page 21-22
  • Dawson. S, Armson. A, Reynoldson. J.A, Thompson. R.C.A, and Mendis. A.H.W. (1992) “Does Giardia duodenalis possess the enzymes to metabolise its glycogen reserves for energy generation?” Proceedings of the First Annual Scientific Meeting of the Fremantle Tropical Medicine Group. (December 1992), page 17-18
  • Mendis. A.H.W, Armson. A and Grubb. W.B. (1991) “Difference spectroscopic characterisation of the cytochrome complement in Acanthocheilonema viteae.” Proceedings of the Aust. Soc. for Parasitol. (October 1991)
  • Mendis. A.H.W, Thompson. R.C.A, Armson. A, and Grubb. W.B. (1991) “The response of Strongyloides ratti infective (L3) larvae to substrates and inhibitors of respiratory electron transport.” Proceedings of the Aust. Soc. for Parasitol. (October 1991)
  • Mendis. A.H.W, Thompson. R.C.A, Reynoldson. J.A, Armson. A, Meloni. B.P. and Gunsberg. S. (1991) “The conversion of L-(U14C-)aspartate to 14CO2 by intact trophozoites of Giardia duodenalis.” Proceedings of the Aust. Soc. for Parasitol. (October 1991)
  • Armson, A, Thompson. R.C.A., Finn, M., Tebbutt, A. And Reynoldson, J.A. Comparison of the effects of dinitroanilines and benzimidazoles on protozoa. Future Chemotherapeutic Targets For The Anaerobic Protozoa, Brisbane,1997 (ICOPA satellite conference).
  • Reynoldson, JA, Armson, A, Thompson, RCA, Finn, M and Tebbutt, A. Antiprotozoal effects of dinitroanilines and benzimidazoles. Thirty-first Annual Scientific Meeting of The Australasian Society Of Clinical and Experimental Pharmacologists and Toxicologists. Canberra, 1997.
  • Armson, A, Finn, M, Pallant, L, Reynoldson, J.A. and Thompson, R.C.A. Multiple tubulin target sites for antiprotozoal drugs, 1998, The American Society of Parasitologists, Hawaii.
  • A Armson, K Sargent, L.M. MacDonald, M Finn, RCA Thompson and JA Reynoldson A Comparison Of The In Vitro And In Vivo Effects Of The Dinitroanilines Oryzalin And Trifluralin Against The Coccidial Parasite Cryptosporidium Parvum. Australasian Society of Chemotherapy and Toxicology Annual Meeting 1999
  • A Armson, K Sargent, L.M. MacDonald, M Finn, RCA Thompson and JA Reynoldson In vitro and in vivo effects of oryzalin and trifluralin against Cryptosporidium parvum Oxford 2000 Meeting
  • Armson, A, Thompson, RCA MacDonald, , LM, Sargent, K, Pallant, L and Reynoldson, JA, An examination of the activity of the dinitroanilines on Cryptosporidium parvum using in vitro, in vivo and target expression methods Cryptosporidium: From Molecules to Disease Meeting, Perth, W. A. June 2001:
  • Armson, A, Menon, K, O’Hara, A, MacDonald, LM, Read, CM, Sargent, K, and Thompson, RCA. Efficacy of oryzalin and associated histological changes in Cryptosporidium infected neonatal rats. COST Conference. London 2002.
  • Read, C., Hobbs, R., Armson, A., Thompson, R.C.A and Reynoldson, J.A. The application of an automatic quantitation system to evaluate drug efficacy against Giadia duodenalis in vitro. The Annual Scientific Meeting of the Australian Society for Parasitology.2002.
  • Low, C.K.A., Armson, A., Thompson, R.C.A and Reynoldson, J.A. Characterisation of Malaria Tubulin Protein for Drug Binding Studies 10th International Congress of Parasitology, Vancouver, Canada.
  • MacDonald, LM, Armson, A, Thompson, RCA and Reynoldson, JA. Expression and characterisation of drug binding sites on the protozoan cytoskeletal protein tubulin. Australian Society for Medical Research Symposium, Perth, W. A.
  • MacDonald, LM, Armson, A, Thompson, RCA and Reynoldson, JA. Expression and characterisation of drug binding sites on the protozoan cytoskeletal protein tubulin. Proceedings of the Fourth International Conference for Molecular and Structural Biology, Vienna, Austria.
  • Pallant, L, MacDonald, LM, Sargent, K, Armson, A, Reynoldson, JA and Thompson, RCA. The application of quantitative-PCR for high throughput screening of novel compounds against Cryptosporidium parvum in vitro and their subsequent IC50 determination. Cryptosporidium: From Molecules to Disease Meeting, Perth, W. A. June 2001:
  • MacDonald, LM, Armson, A, Thompson, RCA and Reynoldson, JA. Validation of the binding site of antimitotic compounds using recombinant protozoan tubulin. Cambridge Healthtech Institute Eleventh Bioinformatics and Genome Research
  • Jayasekera, NS, Armson, A and Stumbles, PA. (2007) The effect of Ross River virus (RRV) infection on the regulation of apoptosis. Abstract submitted to ASMR for presentation Medical Research Week, 2007
  • James, CM, Duffy, S, Pemberton, D, Armson, A and Stumbles, P. (2008) 275 Interferon subtype stimulation of dendritic cells. Key activators of anti-viral immunity. Cytokine 43(3); 309.