Share

Contact me

Phone

(08) 9360 7389

Email

C.Sharp@murdoch.edu.au

Fellow researchers

    Latest news

    • Research
    • School

    Dr Claire Sharp
    BSc, BVMS, MS, DACVECC

    Senior Lecturer

    About me

    I am a senior lecturer in the College of Veterinary Medicine, School of Veterinary and Life Sciences. I did my veterinary training here at Murdoch, graduating with my BSc, BVMS(Hons), in 2002. After a few years in private general and emergency practice in Canberra I moved to the United States to pursue my specialty training. I did a Rotating Small Animal Medicine and Surgery Internship at Oklahoma State University (2004-2005), followed by a Small Animal Emergency and Critical Care Internship at the University of Missouri (2005-2006). I then stayed on at the University of Missouri to complete my Small Animal Emergency and Critical Care Residency and a Masters degree in Veterinary Clinical Sciences (2006-2009). Thereafter I became a Diplomate of the American College of Veterinary Emergency and Critical Care and took a faculty position at the Tufts Cummings School of Veterinary Medicine in North Grafton, Massachusetts where I worked from 2009-2015. I returned to Murdoch for an academic position in July 2015.

    My academic life involves clinical service, teaching and research. I do clinical service in the Murdoch Pet Emergency Centre (MPEC) and Intensive Care unit here at Murdoch. My clinical interests include the management of sepsis, respiratory distress, trauma, gastric dilatation and volvulus amongst many other emergency and critical care diseases. I am particularly challenged by the management of dogs and cats with multiple organ dysfunction syndrome.

    My teaching experience has been diverse including teaching in courses such as immunology, toxicology, biostatistics, cardiovascular physiology and genetics. At Tufts University I co-developed and led a course called Clinical Reasoning to prepare students in their transition between their preclinical and clinical years of eduction. More information about my teaching and research activities is listed below.

    Teaching area

    Currently at Murdoch I teach in the Anesthesia, Emergency and Critical Care (VET452) and Small Animal Medicine (VET456) courses for preclinical veterinary students. My clinical teaching includes the small animal emergency and critical care rotation, and critical care streaming (VET541). In addition, I am involved in supervision of MS students in courses such as Veterinary Case Management (VET675).

    Research areas

    My research interests encompass many aspects of emergency and critical care medicine and beyond, including biomarkers for sepsis and cancer, virology, dog genetics, trauma and coagulation.

    Current projects

    My currently funded research projects are listed below:

     

    Title: An evaluation of antibody titers for feline herpesvirus-1 and feline calicivirus as predictors of the incidence and severity of upper respiratory tract disease in shelter cats

    Funding agency: Maddie’s Shelter Medicine Research Grant

    My role: Principal investigator

    Project description: The major goal of this project are to determine if there is a protective antibody titer to FHV-1 and FCV above which cats presenting to a shelter will not develop clinical signs of upper respiratory tract disease. This grant was written with one of my 2012 summer students.

     

    Title: Investigating feline morbillivirus molecular epidemiology in cats in the North Eastern United States and potential associations with chronic kidney disease

    Funding agency: Winn Feline Foundation

    My role: Principal investigator

    Project description: The major goal of this project is to determine if feline morbillivirus is present in cats in the northeastern USA, via developing an ELISA to look for serum antibodies, and a qPCR protocol to look for viremia. By evaluating cats with and without chronic kidney disease we will attempt to determine an association, as has been suggested in prior studies in South East Asia.

     

    Title: Removal of hemangiosarcoma cells from peritoneal effusion through leukoreduction

    Funding agency: Veterinary Emergency and Critical Care Foundation

    My role: Co-investigator, PI Abelson A

    Project description: The major goals of this project are to determine if commercially available leukoreduction filters can remove neoplastic hemangiosarcoma cells from peritoneal effusion from dogs with a hemoabdomen associated with splenic hemangiosarcoma. Flow cytometry will be used to determine pre- and post-leukoreduction hemangiosarcoma cell numbers.

     

    Title: Application of genomic and molecular methods to understand the pathophysiology of gastric dilatation and volvulus in purebred dogs

    Funding agency: AKC Canine Health Foundation

    My role: Principal investigator

    Project description: The goal of this project is to use a systems biology approach to explain the causality of gastric dilatation and volvulus in dogs. We will evaluate changes in the genome, epigenome, transcriptome, proteome and metabolome in affected and unaffected dogs.

     

    Title: A comparison of the effects of hydroxyethyl starch 130/0.4 and 4% succinylated gelatine on markers of acute kidney injury in a canine hypovolemic shock model

     

    Funding agency: American College of Veterinary Emergency and Critical Care

    My role: Co-investigator, Principal Investigator Smart L

     

     

    Awards and grants

    2014 – Junior Faculty Research Award, Tufts University, Cummings School of Veterinary Medicine

    2011, 2012, 2013 – Compassionate Care Giver Award – The Schwartz Center for Compassionate Health Care

    2009 – Outstanding Resident Award (Faculty Elected), University of Missouri Columbia, College of Veterinary Medicine

    2009 – Resident Mentor Award (Student Elected), University of Missouri Columbia, College of Veterinary Medicine

    2008 – Resident Mentor Award (Student Elected), University of Missouri Columbia, College of Veterinary Medicine

    2005 – Chartered Member of the Australian Veterinary Association

    Events and speaking engagements

    International speaking engagements:

    2016:

    • Western Veterinary Conference, Las Vegas, NV. March 7th-10th, 2016. (8 lecture hours)
    • 2nd annual ACVECC VetCOT Veterinary Trauma and Critical Care Conference. Las Vegas, NV. March 19-20th, 2016.

    2015:

    • American College of Veterinary Emergency and Critical Care (ACVECC) Multidisciplinary Review (MDR). Phoenix, AZ. (4 hours lecture); 2015.
    • Veterinary Emergency and Critical Care Society (VECCS) Spring Break. Costa Rica. (6 hours lecture, 2 hours panel discussion); 2015.
    • American and New Zealand College of Veterinary Scientists, Science Week. Gold Coast (6 hours lecture, 2 hours panel discussion); 2015
    • 7th Tufts’ Canine and Feline Breed and Genetics Conference. Denham MA (1 hour lecture, 1 hour panel discussion Q&A); 2105.
    • International Veterinary Emergency and Critical Care Symposium. Washington DC (5 lecture hours); 2015.

    2014:

    • International Veterinary Emergency and Critical Care Symposium. Indianapolis, IN. (8 hours lecture; 4 hours laboratory); 2014.

    2013:

    • American College of Veterinary Internal Medicine (ACVIM) Forum. Seattle, WA. (1 hours lecture); 2013.
    • International Veterinary Emergency and Critical Care Symposium. San Diego, CA. (1 hours lecture / 4 hours laboratory); 2013.
    • American College of Veterinary Emergency and Critical Care (ACVECC) Multidisciplinary Review (MDR). San Francisco, CA. (1 hours lecture); 2013.

    2012:

    • American College of Veterinary Internal Medicine (ACVIM) Forum, New Orleans, LA. (4 hours lecture); 2012.
    • International Veterinary Emergency and Critical Care Symposium. San Antonio, TX. (7 hours lecture); 2012.

    2011:

    • Emergency Medicine Workshop. University of the West Indies, Trinidad. (7 hours lecture); 2011.
    • International Veterinary Emergency and Critical Care Symposium. Nashville, TN. (3 hours lecture); 2011.

    2010:

    • American College of Veterinary Emergency and Critical Care (ACVECC) Multidisciplinary Review (MDR). Miami, FL. (1 hour lecture); 2010.
    • International Veterinary Emergency and Critical Care Symposium. San Antonio, TX. (8 hour laboratory); 2010.

     

    Publications

    Journals

    • Sharp, C., (2019), Novel viruses: an update on the significance of papillomavirus infections in cats, Journal of Feline Medicine and Surgery, 21, 2019, pages 409 - 418.
    • Yam, E., Boyd, C., Hosgood, G., Claus, M., Raisis, A., Sharp, C., Smart, L., (2019), Hydroxyethyl starch 130/0.4 (6%) and succinylated gelatine (4%) interfere with refractometry in dogs with haemorrhagic shock, Veterinary Anaesthesia and Analgesia, 46, 2019, pages -.
    • Al-Kinani, L., Coiacetto, F., Sharp, C., Rossi, G., Greene, W., (2019), Immunohistochemical Detection of Haemoglobin Subunit Epsilon (HBE) in the Developing Mouse Placenta, Journal of Cytology and Histology, 10, 3, pages -.
    • Sharp, C., (2019), Novel feline viruses: emerging significance of gammaherpesvirus and morbillivirus infections., Journal of Feline Medicine and Surgery, 21, 1, pages 5 - 11.
    • Dorsey, T., Monaghan, K., Respess, M., Labato, M., Babyak, J., Sharp, C., Rozanski, E., deLaforcade, A., (2019), Effect of urinary bladder lavage on in-hospital recurrence of urethral obstruction and durations of urinary catheter retention and hospitalization for male cats, Journal of the American Veterinary Medical Association, 254, 4, pages 483 - 486.
    • Boyd, C., Claus, M., Raisis, A., Ciancolo, R., Bosio, E., Hosgood, G., Nabity, M., Mori, T., Barden, A., Sharp, C., Smart, L., (2019), Evaluation of biomarkers of kidney injury following 4%succinylated gelatin and 6%hydroxyethyl starch 130/0.4 administration in a canine hemorrhagic shockmodel, Journal of Veterinary Emergency and Critical Care, 29, 2, pages 132 - 142.
    • Goggs, R., Blais, M., Brainard, B., Chan, D., deLaforcade, A., Rozanski, E., Sharp, C., (2019), American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE) guidelines: Small animal, Journal of Veterinary Emergency and Critical Care, 29, 1, pages 12 - 36.
    • Sharp, C., Goggs, R., Blais, M., Brainard, B., Chan, D., deLaforcade, A., Rozanski, E., (2019), Clinical application of the American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE) guidelines to small animal cases, Journal of Veterinary Emergency and Critical Care, 29, 2, pages 121 - 131.
    • Blais, M., Bianco, D., Goggs, R., Lynch, A., Palmer, L., Ralph, A., Sharp, C., (2019), Consensus on the Rational Use of Antithrombotics inVeterinary Critical Care (CURATIVE): Domain 3Defining antithrombotic protocols, Journal of Veterinary Emergency and Critical Care, 29, 1, pages 60 - 74.
    • Sharp, C., deLaforcade, A., Koenigshof, A., Lynch, A., Thomason, J., (2019), Consensus on the Rational Use of Antithrombotics inVeterinary Critical Care (CURATIVE): Domain 4Refining and monitoring antithrombotic therapies, Journal of Veterinary Emergency and Critical Care, 29, 1, pages 75 - 87.
    • Garden, O., Kidd, L., Mexas, A., Chang, Y., Jeffery, U., Blois, S., Fogle, J., MacNeill, A., Lubas, G., Birkenheuer, A., Buoncompagni, S., Dandrieux, J., Di Loria, A., Fellman, C., Glanemann, B., Goggs, R., Granick, J., LeVine, D., Sharp, C., Smith-Carr, S., Swann, J., Szladovits, B., (2019), ACVIM consensus statement on the diagnosis of immunemediated hemolytic anemia in dogs and cats, Journal of Veterinary Internal Medicine, 33, 2, pages 313 - 334.
    • Boyd, C., Claus, M., Raisis, A., Hosgood, G., Sharp, C., Smart, L., (2018), Hypocoagulability and platelet dysfunction are exacerbated by synthetic colloids in a canine hemorrhagic shock model, Frontiers in Veterinary Science, 5, NOV, pages 279 -.
    • Sharp, C., (2018), Maternal-fetal blood crossmatching in sheep. Comparative Medicine, Comparative Medicine: animal models in biomedical research, 68, 4, pages 294 - 297.
    • Rozanski, E., Sharp, C., Babyak, J., de Laforcade, A., (2018), Evaluation of thromboelastography in bitches with pyometra, Journal of Veterinary Diagnostic Investigation, 30, 1, pages 165 - 168.
    • Musk, G., Adams, M., Usuda, H., Kemp, M., Sharp, C., (2018), Crossmatching Maternal and Fetal Blood in Sheep, Comparative Medicine: animal models in biomedical research, 68, 4, pages 294 - 297.
    • Boller, M., McMichael, M., Sharp, C., (2018), ACVECCs Veterinary Committee on Trauma (VetCOT) Registry subcommittee. ACVECC-Veterinary Committee on Trauma Registry Report 2013-2017, Journal of Veterinary Emergency and Critical Care, 28, 6, pages 497 - 502.
    • Sharp, C., (2018), Veterinary students knowledge and perceptions about antimicrobial stewardship and biosecurity; a national survey., Journal of Antibiotics: an international journal devoted to research on bioactive microbial products, 7, 2, pages ppii - E34.
    • Babyak, J., Weiner, D., Noubary, F., Sharp, C., (2017), Prevalence of Elevated Serum Creatinine Concentration in Dogs Presenting to a Veterinary Academic Medical Center (20102014), Journal of Veterinary Internal Medicine, online, , pages -.
    • Babyak, J., Weiner, D., Noubary, F., Sharp, C., (2017), The prevalence of elevated creatinine in dogs presenting to a veterinary academic medical center (2010-2014), Journal of Veterinary Internal Medicine, , , pages -.
    • Mukherjee, J., Sharp, C., (2017), Evaluation of the sterility of single-dose medications used in a multi-dose fashion, a pilot study, The Canadian Veterinary Journal, 58, 11, pages 1187 - 1190.
    • Aona, B., Rush, J., Rozanski, E., Cunningham, S., Sharp, C., Freeman, L., (2017), Evaluation of echocardiography and cardiac biomarker concentrations in dogs with gastric dilatation volvulus, Journal of Veterinary Emergency and Critical Care, 27, 6, pages 631 - 637.
    • Turpin, D., Lagendijk, P., Sharp, C., Pluske, J., (2017), Improving welfare and production in the peri-weaning period: Effects of comingling and intermittent suckling on the stress response, performance, behaviour, and gastrointestinal tract carbohydrate absorption in young pigs, Livestock Science, 203, 2017, pages 82 - 91.
    • Babyak, J., Sharp, C., (2016), Epidemiology of systemic inflammatory response syndrome and sepsis in cats hospitalized in a veterinary teaching hospital, Journal of the American Veterinary Medical Association, 249, 1, pages 65 - 71.
    • Sharp, C., Cummings, K., Rozanski, E., Abelson, A., (2016), The effect of storage on ammonia, cytokine, and chemokine concentrations in feline whole blood, Journal of Veterinary Emergency and Critical Care, 26, 5, pages 639 - 645.