Hamid Sohrabi  from Murdoch University in Perth Australia.
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Phone

+61 8 9360 6901

Email

Hamid.Sohrabi@murdoch.edu.au

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    Associate Professor Hamid Sohrabi
    BSc, MSc, PhD

    Director, Centre For Healthy Ageing

    About me

    Over the last 15 years, I have developed a track record in Alzheimer’s disease (AD) research. I began my career as a Clinical Psychologist and completed my PhD in Psychiatry and Clinical Neurosciences at the University of Western Australia (2010). As a Neuroscientist/Clinical Psychologist, my current research seeks to translate knowledge obtained from clinical and cognitive neurosciences into screening and diagnostic measures for pre-clinical and prodromal stages of AD as well as preventive interventions to halt pathological cognitive decline and dementia. I will be pleased to consider applications from prospective PhD students who are interested in psychological and neuroscience research on ageing, cognition, and dementia.

    Teaching area

    Psychology of Ageing (PSY382)

    Research areas

    My research is focused on cognitive and psychological ageing, dementia, and Alzheimer’s disease. I am also interested in understanding the underlying mechanisms of healthy ageing; that is how people can enjoy an independent lifestyle despite age-related changes.

    Honours and PhD projects are available on healthy ageing, clinical geropsychology, dementia and Alzheimer’s disease.

    Current projects

    Some of the projects that I am involved in:

    1.The Molecular and Neuropsychological Predictive Markers of Cognitive Decline (WA Memory Study (WAMS)): This is an ongoing, longitudinal study to examine clinical, cognitive, neurobiopsychosocial changes that are associated with ageing in individuals aged 40 years old and above.

    2. Testosterone and DHA (Omega 3) on Amyloid Load in brain (TotAL Study): This study is a randomised double-blind clinical trial on prevention of Alzheimer’s disease in older men by using testosterone with or without fish oil. All participants have to be positive for brain amyloid imaging, as a marker of Alzheimer’s disease neuropathology.

    3. The AUstralian multidomain Approach to Reduce dementia Risk by protecting brain health With lifestyle intervention study (AU-ARROW): This study is a multi-modal preventive project aimed at utilising lifestyle changes to prevent dementia syndrome in individuals at higher risk of Alzheimer’s disease. 

    4. The Dominantly Inherited Alzheimer Network (DIAN) Study: The DIAN Study is an international, multi-centre, longitudinal project examining the progress of Alzheimer’s disease clinical, blood, CSF and imaging biomarkers in individuals with or without mutations causing Alzheimer’s in individuals from families with such mutations.

    5. Alzheimer’s Dementia Onset and Progression in International Cohorts (ADOPIC): This is an international collaboration leveraging the power of five leading Alzheimer’s cohorts worldwide to clarify risk and protective factors for Alzheimer’s dementia (AD) and related disorders: the Adult Children Study (ACS), the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Australian Imaging, Biomarkers and Lifestyle Study (AIBL), the Dominantly Inherited Alzheimer Network (DIAN) and the National Alzheimer’s Coordinating Center (NACC).

    Awards and grants

    Successful grants over the last 5 years:

    1)  The AUstralian-multidomain Approach to Reduce dementia Risk by prOtecting brain health With lifestyle intervention (AU-ARROW) Study; Martins, R., Primary Chief Investigator, Anstey, K. J., Chief Investigator, Naismith, S., Chief Investigator, Baker, L. D., Chief Investigator, Kivipelto, M., Chief Investigator, Sohrabi, H.R., Chief Investigator, Burnham, S., Chief Investigator, Villemagne, V., Chief Investigator, Grieve, S. M., Chief Investigator, Yates, P. A., Chief Investigator, Funding Agency, NHMRC-MRFF, Department of Health (Commonwealth): AU$4,194,115.90; 2019 → 2024.

    2)  Investigating the diagnostic utility of hyperspectral retinal imaging in preclinical Alzheimer’s disease;  Martins, R., Primary Chief Investigator, Graham, S. L., Chief Investigator, Gillatt, D., Chief Investigator, Shah, T., Associate Investigator, Gupta, S., Associate Investigator, Chatterjee, P., Associate Investigator, Sohrabi, H.R., Associate Investigator, Goozee, K., Associate Investigator; Optina Diagnostics Inc: AUD$250,000.00; 2017-2019.

    3)  Dementia Grants Program– New and Early Career Research Project Grants; Dr Hakuei Fujiyama ((CIA)), and A/Prof Hamid Sohrabi, Dr Mark Hinder, and Professor Michael Nitsche as Associate Investigators; AU$50,000; 2018-2019.

    4)  Chemrez Technologies and Macquarie University combined funding to investigate the “Effect of CocoMCT® on Clinical Factors related to Health, Cognition, Quality of Life and Alzheimer’s disease-related Biomarkers; Martins, R., Primary Chief Investigator, Chatterjee, P., Chief Investigator, Sohrabi, H.R., Chief Investigator, Bacsi, A., Chief Investigator, Goozee, K., Associate Investigator; Macquarie University: AU$75,000.00, Chemrez Technologies, Inc: AU$250,000.00; 2017-2020.

    5)  The Cecilia Margaret Hudson Dementia Research Grant; Alzheimer’s Australia; A/Prof Hamid Sohrabi (CIA) and Prof Ralph Martins, Dr Tejal Shah, and Dr Sunil Gupta as Associate Investigators; AU$50,000; 2015-2016.

    Publications

  • Complete publications list:

  • https://orcid.org/0000-0001-8017-8682
  • https://www.researchgate.net/profile/Hamid_Sohrabi
  • https://scholar.google.com.au/citations?user=tgZfiJwAAAAJ&hl=en
  • Most recent publications:
  • Sohrabi, Hamid R.; Goozee, Kathryn; Weinborn, Michael; Shen, Kaikai; Brown, Belinda; Rainey-Smith, Stephanie; Salvado, Olivier; Maruff, Paul; and et al., (2020). Personality factors and cerebral glucose metabolism in community-dwelling older adults without cognitive impairment; Brain Structure & Function; 225:1511–1522.
  • Brini, Stefano  ; Sohrabi, Hamid R. ; Hebert, Jeffrey J. ; Forrest, Mitchell R. L. ; Laine, Matti ; Hamalainen, Heikki ; Karrasch, Mira ; Peiffer, Jeremiah J.  ; Martins, Ralph N. ; Fairchild, Timothy J., (2020). Bilingualism Is Associated with a Delayed Onset of Dementia but Not with a Lower Risk of Developing it: A Systematic Review with Meta-Analyses. Neuropsychology Review; 30:1-24.
  • Chatterjee, Pratishtha  ; Fernando, Malika ; Fernando, Binosha  ; Dias, Cintia B.  ; Shah, Tejal ; Silva, Renuka ; Williams, Shehan ; Pedrini, Steve  ; Hillebrandt, Heidi  ; Goozee, Kathryn  ; Barin, Edward  ; Sohrabi, Hamid R. ; Garg, Manohar ; Cunnane, Stephen  ; Martins, Ralph N., (2020). Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer’s disease. Mechanisms of Ageing and Development; 186: 111209.
  • Tan, S., Sohrabi, H. R., Weinborn, M., Tegg, M., Bucks, R. S., Taddei, K., … Martins, R. N., (2019). Effects of testosterone supplementation on separate cognitive domains in cognitively healthy older men: a meta-analysis of current randomized clinical trials. American Journal of Geriatric Psychiatry; 27: 1232-1246.
  • Porter, T., Burnham, S. C., Milicic, L., Savage, G., Maruff, P., Sohrabi, H. R., Peretti, M., …, Laws, S.M., (2019). COMT val158met is not associated with Aβ-amyloid and APOE ε4 related cognitive decline in cognitively normal older adults. IBRO Reports; 6: 147-152.
  • Chatterjee, Pratishtha ; Elmi, Mitra ; Goozee, Kathryn ; Shah, Tejal ; Sohrabi, Hamid R. ; Dias, Cintia B. ; Pedrini, Steve ; Shen, Kaikai ; Asih, Prita R. ; Dave, Preeti ; Taddei, Kevin ; Vanderstichele, Hugo ; Zetterberg, Henrik ; Blennow, Kaj ; Martins, Ralph N., (2019). Ultrasensitive detection of plasma amyloid-β as a biomarker for cognitively normal elderly individuals at risk of Alzheimer’s disease. Journal of Alzheimer’s Disease; 71:775–783.
  • Dang, C., Yassi, N., Harrington, K., Xia, Y., Lim, Y. Y., Ames, D., Laws, S., Hickey, M., Rainey-Smith, S., Sohrabi, H. R., Doecke, J. D., Fripp, J., Salvado, O., Weinborn, M., Villemagne, V., Rowe, C. C., Masters, C. L., & Maruff, P., for the AIBL Research Group., (2019). Rates of age- and amyloid β-associated cortical atrophy in older adults with superior memory performance. Alzheimer’s & Dementia: Diagnosis, Assessment and Disease Monitoring;  11: 566-575.
  • Marston, Kieran J; Peiffer, Jeremiah J; Rainey-Smith, Stephanie R; Gordon, Nicole; Teo, Shaun Y; Laws, Simon M; Sohrabi, Hamid R; Martins, Ralph N; and Brown, Belinda M., (2019). Resistance training enhances delayed memory in healthy adults: A randomised controlled trial; Journal of Science and Medicine in Sport; 22: 1226-1231.
  • Schultz, A.; Kloet, R.; Sohrabi, H.; van der Weerd, L.; van Rooden, S.; Wermer, M.; Grand Moursel, L.; Yaqub, M.; Van Berckel, .; Chatterjee, P.; Gardener, S.; Taddei, K.; Fagan, A.; Benzinger, T.; Morris, J.; Sperling, R.; Johnson, K.; Bateman, R.; Gurol, M. E.; van Buchem, M.; Martins, R.; Chhatwal, J.; Greenberg, S., (2019). Amyloid Imaging of Dutch-type Hereditary Cerebral Amyloid Angiopathy Carriers; Annals of Neurology; 86: 616-625.
  • Tan, J., Iyer, K. K., Tang, A. D., Jamil, A., Martins, R. N., Sohrabi, H. R., … & Fujiyama, H., (2019). Modulating functional connectivity with non-invasive brain stimulation for the investigation and alleviation of age-associated declines in response inhibition: A narrative review. NeuroImage; 185: 490-512.
  • Frost, N., Weinborn, M., Gignac, G. E., Markovic, S., Rainey-Smith, S. R., Sohrabi, H. R., … & Brown, B. M., (2019). Higher Cardiorespiratory Fitness is Associated with Better Verbal Generativity in Community Dwelling Older Adults. Journal of Aging and Physical Activity; 27: 703-710.
  • Fine, L., Weinborn, M., Ng, A., Loft, S., Li, Y.R., Hodgson, E., Parker, D., Rainey Smith, S., Sohrabi, H.R., Brown, B. and Martins, R., Bucks, R. S., (2019). Sleep disruption explains age-related prospective memory deficits: implications for cognitive aging and intervention. Aging, Neuropsychology, and Cognition; 26: 621-636.
  • Sohrabi, H. R., Weinborn, M., Laske, C., Bates, K. A., Christensen, D., Taddei, K., … & Martins, R.N., (2019). Subjective memory complaints predict baseline but not future cognitive function over three years: results from the Western Australia Memory Study. International Psychogeriatrics; 31: 513-525.
  • Babulal, G.M., Quiroz, Y.T., Albensi, B.C., Arenaza-Urquijo, E., Astell, A.J., Babiloni, C., Bahar-Fuchs, A., Bell, J., Bowman, G.L., Brickman, A.M.,…, Sohrabi, H.R. et al. on behalf of the International Society to Advance Alzheimer’s Research and Treatment, Alzheimer’s Association, (2019). Perspectives on ethnic and racial disparities in Alzheimer’s disease and related dementias: Update and areas of immediate need. Alzheimer’s & Dementia; 15: 292-312.