Dr Nicola Armstrong
BSc(Hons), PhD

Senior Lecturer

About me

I received my PhD from the Department of Statistics at UC Berkeley. After graduating, I moved to the Netherlands where I spent time as a post doc at Eurandom and the Vrije Universiteit before moving to the Netherlands Cancer Institute in Amsterdam as a senior statistician. On returning to Australia in 2009, I spent time at the Garvan Institute and the School of Mathematics and Statistics at the University of Sydney before moving to Murdoch in 2015.

Teaching area

Semester 2 2017:

  • MAS353 Statistical Design and Data Analysis
  • BIF Bioinformatics (BCA)

Units I have taught at Murdoch:

  • MAS222 Probability and Statistical Inference
  • MAS224 Biostatistical Methods

Other units (Biostatistics Collaboration of Australia)

  • BIF Bioinformatics

Research areas

My research concerns the application of statistics to genomics. In particular, I am interested in:

  • statistical genetics;
  • epigenetics;
  • genomic data integration.

Awards and grants

GRANTS

  • 2016 France-Australia Science Innovation Collaboration (FASIC) Fellowship
  • 2016-18 NHMRC National Institute for Dementia Research: “A European DNA bank for deciphering the missing heritability of Alzheimer’s disease (EADB)”, $1.56m, Chief Investigator.
  • 2016-18 NHMRC National Institute for Dementia Research: “BRIDGET: BRain imaging, cognition, Dementia and next generation GEnomics: a Transdisciplinary search for risk and protective factors of neurodegenerative disease”, $1.08m, Chief Investigator.
  • 2015 Mason Foundation grant: “Using an integrated ‘omics approach to better understand AD development”, $58,000, Chief Investigator.
  • 2015 SEIT small equipment grant: “Mathematics and Statistics research server”, $26,000, Chief Investigator.
  • 2015 NSW Office of Science and Research Conference grant, “ABACBS 2015
  • 2003 Exchange grant, Programme on Integrated Approaches for Functional Genomics, ESF.

AWARDS

  • Hewlett Foundation Fellowship at UC Berkeley, 1996/7.
  • Statistical Society of Australia (WA) Honors Fellowship, 1994.
  • Australian Bureau of Statistics cadet, 1994.
  • University Medalist in Science, Murdoch University, 1993.

Events and speaking engagements

Since 2008:

  • BioInfoSummer 2017 (Invited Speaker)
  • Women in Mathematics 2017 (Invited Speaker)
  • Australian Statistics Conference 2016 (Invited Speaker)
  • Statistical Society of Australia, WA branch (Invited Speaker)
  • GeneMappers 2015 (Speaker selected from abstracts)
  • Mathematics and Statistics, Murdoch University, 2014 (Invited Speaker)
  • AGTA 2014 (Speaker selected from abstracts)
  • Joint Statistical Meetings 2013 (Invited Speaker)
  • CMIS division seminar, CSIRO 2013 (Invited Speaker)
  • Australian Statistics Conference 2010 (Invited Speaker, Speaker selected from abstracts)
  • School of Mathematics and Statistics, University of New South Wales 2010, 2014 (Invited Speaker)
  • Cancer Research Program, Garvan Institute of Medical Research 2009 (Invited Speaker)
  • School of Mathematics and Statistics, University of Sydney 2009 (Invited Speaker)
  • Eurandom: A random tour through a decade of research 2008 (Invited Speaker)

Professional and community service

Current:

  • Member, Program committee InCoB (since 2012)
  • Member, ABACBS executive committee (since 2016)
  • Member, AMSI Research and Higher Education Committee (since 2016)
  • Member, AMSI BioInfoSummer standing committee (since 2016)

Past:

  • Co-convenor, ABACBS 2015
  • Co-organiser, BioInfoSummer 2015
  • Chair, Organising committee Sydney Bioinformatics Research Symposium (2011-2014)
  • Co-ordinator, Bioinformatics User Group, Garvan Institute of Medical Research (2011-2013)
  • Member/Chair, PostDoc Development Committee, Garvan Institute of Medical Research (2012-13)
  • Member, NHMRC PostDoc Reference Panel (2012-2015)
  • Member, NHMRC GRP (2017)

Professional Memberships:

  • Royal Statistical Society
  • Statistical Society of Australia
  • Australian Bioinformatics And Computational Biology Society (ABACBS)

Doctoral and masters supervisions

Primary supervision

  • Novia Minaee (PhD, current)

Co-supervision

  • Ross Bowden (PhD, current): Modelling Joint Autoregressive Moving Average Processes
  • Dario Strbenac (PhD, completed 2016, University of Sydney): Novel Summaries for Omics Data Types and Their Performance Evaluation

Publications

Preprints

  • Kong XZ, Mathias S, Guadalupe T, Abé C, Agartz I, Akudjedu TN, Aleman A, Alhusaini S, Allen NB, Ames D, Andreassen OA, Armstrong NJ, Bergo F et al. Mapping Cortical Brain Asymmetry in 17,141 Healthy Individuals Worldwide via the ENIGMA Consortium. bioRxiv 196634; doi: https://doi.org/10.1101/196634
  • Satizabal CL, Adams HHH, Hibar DP, White CC, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivieres S, Arias-Vasquez A, Chauhan G, Athanasiu L, Renteria ME, Kim S, Hohn D, Armstrong NJ, Chen Q et al. Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide. bioRxiv 173831; doi: https://doi.org/10.1101/173831

Publications

  • Karlsson Linner R, Marioni R, Simpkin A, Davies NM, Watanabe K, Armstrong NJ, Auro K, Baumbach C, Bonder MJ et al. An epigenome-wide association study meta-analysis of educational attainment. Accepted, Mol Psych 22/08/17.
  • Strbenac D, Zhong L, Raftery MJ, Wang P, Wilson SR, Armstrong NJ, Yang JYH. Quantitative performance evaluator for proteomics (QPEP): Web-based application for reproducible evaluation of proteomics preprocessing methods. J Proteome Res, 2017,16(7):2359-2369.
  • Armstrong NJ, Mather KA, Thalamuthu A, Wright MJ, Trollor JN, Ames D, Brodaty H, Schofield PR, Sachdev PS, Kwok JB. Ageing, exceptional longevity and comparisons of the Hannum and Horvath epigenetic clocks. Epigenomics, 2017, 9(5):689-700.
  • Guadalupe T, Mathias SR, vanErp TG, Whelan CD, Zwiers MP, Abe Y, Abramovic L, Agartz I, Andreassen OA, Arias-Vásquez A, Aribisala BS, Armstrong NJ, Arolt V et al. Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. Accepted, Brain Imaging Behav, 10/16.
  • Hibar D, Adams H, Jahanshad N, Chauhan G, Stein J, Hofer E, Rentería M, Bis J, Arias-Vasquez A, Ikram MK, Desrivieres S, Vernooij M, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala B, Armstrong NJ, Athanasiu L et al. Novel genetic loci associated with hippocampal volume. Nature Comms, 2017, 8:13624.
  • Stirzaker C, Song J, Ng W, Du Q, Armstrong NJ, Locke W, Statham A, Pidsley R, Valdes-Mora F, French F, Zotenko E, Clark S. Methyl-CpG-Binding Protein MBD2 plays a key role in maintenance and spread of DNA methylation of CpG islands and shores in cancer. Oncogene, 2017, 36(10):1328-1338.
  • Tran DN, Smith SABC, Brown DA, Parker AJC, Joseph JE, Armstrong NJ, Sewell WA. Polychromatic flow cytometry is more sensitive than microscopy in detecting small monoclonal plasma cell populations. Cytometry: Part B – Clinical Cytometry, 2017 92(2):136-144.
  • Mather KA, Armstrong NJ, Thalamuthu A, Kwok JB. Tick tock: DNA methylation, the epigenetic clock and exceptional longevity. Epigenomics, 2016 8(12):1577-1582.
  • Adams HHH, Hibar DP, Chouraki V, Stein JL, Nyquist P, Renteria ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis KA, Aribisala BS, Armstrong NJ, Athanasiu L et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience, 2016, 19(12):1569-1582.
  • Mather K, Thalamuthu A, Oldmeadow C, Song F, Armstrong N, Poljak A, Holliday E, McEvoy M, Kwok JBJ, Assareh A, Reppermund S, Kochan N, Lee T, Ames D, Wright M, Trollor J, Schofield P, Brodaty H, Scott R, Schofield PR, Attia J, Sachdev P. Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults. Scientific Reports, 2016 6:23675.
  • Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Yao Y, Ho YY, Martin NG, Wright MJ; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Psychosis Endophenotypes International Consortium; Wellcome Trust Case Control Consortium 2; Enigma Consortium, O’Donovan MC, Thompson PM, Neale BM, Medland SE, Sullivan PF. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nature Neuroscience, 2016 19(3):420-31.
  • Lupton MK, Strike L, Hansell NK, Wen W, Mather KA, Armstrong NJ, Thalamuthu A et al. The effect of increased genetic risk for Alzheimer’s disease on hippocampal and amygdala volume. Neurobiology of Aging, 2016 40:68-77.
  • Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Schmidt CO, Mather KA, Chouraki V, Sun Q, Resnick SM, Rose LM, Oldmeadow C, Stewart M, Smith BH, Gudnason V, Yang Q, Mirza SS, Jukema JW, deJager PL, Harris TB, Liewald DC, Amin N, Coker LH, Stegle O, Lopez OL, Schmidt R, Teumer A, Ford I, Karbalai N, Becker JT, Jonsdottir MK, Au R, Fehrmann RSN, Herms S, Nalls M, Zhao W, Turner ST, Yaffe K, Lohman K, van Swieten JC, Kardia SLR, Knopman DS, Meeks WM, Heiss G, Holliday EG, Schofield PW, Tanaka T, Stott DJ, Wang J, Ridker P, Gow AJ, Pattie A, Starr JM, Hocking LJ, Armstrong NJ, et al. GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Molecular Psychiatry, 2016 21(2):189-97.
  • Tan J, Armstrong NJ, Yuan FF, Flower RL, Dyer WB. Identification of genetic polymorphisms that predict responder/non-responder profiles to the RhD antigen. Molecular Immunology, 2015 68(2 Pt C):628-33.
  • Boraxbekk CJ, Ames D, Kochan NA, Lee T, Thalamuthu A, Wen W, Armstrong NJ, Kwok JB, Schofield PR, Reppermund S, Wright MJ, Trollor JN, Brodaty H, Sachdev P, Mather KA. Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals. Neuropsychologia 2015 78:10-7.
  • Wu HZY, Ong KL, Seeher K, Armstrong NJ, Thalamuthu A, Brodaty H, Sachdev P, Mather K. Circulating microRNAs as biomarkers of Alzheimer’s disease – a systematic review. Journal of Alzheimer’s Disease 2015 49(3):755-66
  • Matuszek MA, Anton A, Thillainathan S, Armstrong NJ. Increased insulin following an oral glucose load, genetic variation near the melatonin receptor MTNR1B, but no biochemical evidence of endothelial dysfunction in young Asian men and women. PLoS ONE, 2015 10(7):e0133611.
  • Hibar D, Stein J, Renteria M, Arias-Vasquez A, Desrivieres S, Jahanshad N, Toro R, Wittfeld K, Andersson M, Aribisala B, Armstrong N et al. Common genetic variants influence human subcortical brain structures. Nature, 2015 520(7546):224-9
  • Stirzaker C, Zotenko E, Song J, Qu W, Nair S, Locke WJ, Stone A, Armstrong N, Robinson M, Dobrovic A, Avery-Kiejda K, Peters K, French J, Stein S, Korbie D, Trau M, Forbes J, Scott R, Brown MA, Francis G, Clark S. Methylome sequencing in triple negative breast cancer reveals distinct methylation clusters with prognostic value. Nature Communications, 2015 6:5899.
  • Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, DeStefano AL, de Quervain DJF, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell H, Petrovic K, Fornage M, Chauhan G, Yeo R, Boxall R, Becker J, Stegle O, Mather KA, Chouraki V, Sun Q, Rose LM, Resnick S, Oldmeadow C, Kirin M, Wright AF, Jonsdottir MK, Au R, Becker A, Amin N, Nalls MA, Turner ST, Kardia SLR, Oostra B, Windham G, Coker LH, Zhao W, Knopman DS, Heiss G, Griswold ME, Gottesman RF, Vitart V, Hastie ND, Zgaga L, Rudan I, Polasek O, Holliday EG, Schofield P, Choi SH, Tanaka T, An Y, Perry RT, Kennedy RE, Sale MM, Wang J, Wadley VG, Liewald DC, Ridker PM, Gow AJ, Pattie A, Starr JM, Porteous D, Liu X, Thomson R, Armstrong NJ, et al. Genome-wide studies of verbal declarative memory in non-demented older people: the CHARGE consortium.  Biol Psychiatry, 2015 77(8):749-63.
  • Eslam M, Hashem AM, Leung R, Romero-Gomez M, Berg T, Dore GJ, Chan HLY, Irving WL, Sheridan D, Abate ML, Adams LA, Mangia A, Weltman M, Bugianesi E, Spengler U, Shaker O, Fischer J, Mollison L, Cheng W, Powell E, Nattermann J, Riordan S, McLeod D, Armstrong NJ, Douglas MW, Liddle C, Booth DR, George J, Ahlenstiel G for the International Hepatitis C Genetics Consortium (IHCGC). Interferon lambda rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease. Nature Communications, 2015 6:6422.
  • Chan JPL, Thalamuthu A, Oldmeadow C, Armstrong NJ, Holliday EG, McEvoy M, Kwok JB, Assareh AA, Peel R, Hancock SJ, Reppermund S, Menant J, Trollor JN, Brodaty H, Schofield PR, Attia JR, Sachdev PS, Scott RJ, Mather KA. Genetics of Hand Grip Strength in Mid to Late Life. AGE, 2015 37(1):9745.
  • Lazarus J,Mather KA, Armstrong NJ, Song F, Poljak A, Thalamuthu A,Lee T, Kochan NA, Brodaty H, Wright MJ, Ames D, Sachdev PS, Kwok JBJ. DNA Methylation in the Apolipoprotein-A1 Gene is Associated with Episodic Memory Performance in Healthy Older Individuals. Journal of Alzheimer’s Disease, 2015 44(1):175-82.
  • Zhou J, Belov L, Chapuis P, Chan C, Armstrong NJ, Kaufman KL, Solomon MJ, Clarke SJ, Christopherson R. Surface profiles of live colorectal cancer cells and tumour infiltrating lymphocytes from surgical samples correspond to prognostic categories. Journal of Immunological Methods, 2015 416:59-68.
  • Mather KA, Armstrong NJ, Wen W, Kwok JB, Assareh A, Thalamuthu A, Reppermund S, Duesing K, Wright MJ, Ames D, Trollor JN, Brodaty H, Schofield PR, Sachdev PS. Investigating the genetics of hippocampal volume in older adults. PLoS ONE, 2015 10(1):e0116920.
  • Davies G, Armstrong N, Bis J, Bressler J et al. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE Consortium (N = 53 949). Molecular Psychiatry, 2015 20(2):183-92
  • Kirschner M, Cheng YY, Armstrong NJ, Lin RC, Kao SC, Linton A, Klebe S, McCaughan BC, van Zandwijk N, Reid G. MiR-Score: A novel 6-microRNA signature that predicts survival outcomes in patients with malignant pleural mesothelioma. Molecular Oncology, 2015 9(3):715-26.
  • Ali NA, Wu J, Hochgrafe F, Chan H, Nair R, Ye S, Zhang L, Lyons RJ, Pinese M, Lee HC, Armstrong NJ, Ormandy CJ, Clark SJ, Swarbrick A, Daly RJ. Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signaling networks and conserved oncogenic pathways. Br Cancer Res, 2014 16(5):R437.
  • Kaufman KL, Mactier S, Armstrong NJ, Mallawaaratchy D, Byrne S, Haydu L, Jakrot V, Thompson JF, Mann GJ, Scolyer RA, Christopherson RI. Surface antigen profiles of leukocytes and melanoma cells in lymph nodes correlate with survival in AJCC stage III metastatic melanoma patients. Clinical and Experimental Metastasis, 2014 31(4):407-421.
  • Ising M, Mather K, Zimmermann P, Brückl T, Höhne N, Heck A, Schenk L, Rujescu D, Armstrong N, Sachdev P, Reppermund S. Genetic effects on information processing speed are moderated by age – converging results from 3 samples. Genes Brain Behav, 2014 13(5):501-507.
  • Coupland KG, Mellick GD, Silburn PA, Mather K, Armstrong NJ, Sachdev PS, Brodaty H, Huang Y, Halliday GM, Hallupp M, Kim WS, Dobson-Stone C, Kwok JB. DNA methylation of the MAPT gene in Parkinson’s disease cohorts and modulation by vitamin E in vitro. Mov Disord., 2014 29(13):1606-14.
  • Mather KA, Armstrong N, Kwok JB, Sachdev PS. The role of epigenetics in cognitive ageing. Int J Geriatr Psychiatry, 2014 29(11):1162-71.
  • Warton K, Lin V, Navin T, Armstrong NJ, Kaplan W, Ying K, Gloss B, Mangs H, Nair SS, Hacker NF, Sutherland RL, Clark SJ, Samimi G. Methylation-capture and next-generation sequencing of free circulating DNA from human plasma. BMC Genomics, 2014 15(1):476.
  • Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, et al. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav, 2014 8(2):153-182.
  • Nair R, Roden DL, Teo WS, McFarland A, Junankar S, Ye S, Nguyen A, Yang J, Nikolic I, Hui M, Morey A, Shah J, Pfefferle AD, Usary J, Selinger C, Baker LA, Armstrong N, Cowley MJ, Naylor MJ, Ormandy CJ, Lakhani SR, Herschkowitz JI, Perou CM, Kaplan W, O’Toole SA, Swarbrick A. c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer. Oncogene, 2014 33(30):3992-4002
  • Dobson-Stone C, Polly P, Korgaonkar MS, Williams LM, Gordon E, Schofield PR, Mather K, Armstrong NJ, Wen W, Sachdev PS, Kwok JBJ. GSK3B and MAPT polymorphisms are associated with grey matter and intracranial volume in healthy individuals. PLoS ONE, 2013 8(8):e71750
  • Strbenac D, Armstrong NJ, Yang JYH. Detection and classification of peaks in 5’ cap RNA sequencing data. BMC Genomics, 2013 14 Suppl 5:S9.
  • Parnell GP, Tang BM, Nalos M, Armstrong NJ, Huang SJ, Booth DR, McLean AS. Identifying key regulatory genes in the whole blood of septic patients to monitor underlying immune dysfunctions. Shock, 2013 40(3):166-174
  • Suppiah V, Armstrong NJ, O’Connor KS, Berg T, Weltman M, Abate ML, Spengler U, Bassendine M, Dore GJ, Irving WL, Powell E, Nattermann J, Muller T, Riordan S, Stewart GJ, George J, Booth DR, Ahlenstiel G, for the International Hepatitis C Genetics Consortium (IHCGC). CCR5-Δ32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection. Genes and Immunity, 2013 14(5):286-290
  • Hulf T, Sibbritt T, Wiklund ED, Patterson K, Song JZ, Stirzaker C, Qu W, Nair S, Horvath LG, Armstrong NJ, Kench JG, Sutherland RL, Clark SJ. Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer. Oncogene, 2013 32(23):2891-9.
  • Zhou J, Belov L, Armstrong NJ, Christopherson RI. Antibody microarray and multiplexing. In Bioinformatics of Human Proteomics, Springer, 2013.
  • Kalyuga M, Gallego-Ortega D, Lee HJ, Roden D, Cowley MJ, Caldon CE, Stone A, Allerdice SL, Valdes-Mora F, Launchbury R, Statham A, Armstrong NJ, Alles C, Young A, Egger A, Au W, Piggin C, Evans C, Ledger A, Brummer T, Oakes SR, Kaplan W, Gee JMW, Nicholson RI, Sutherland RL, Swarbrick A, Naylor NJ, Clark S, Carroll JS, Ormandy CJ. ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. PLoS Biology, 2012 10(12):e1001461.
  • Parnell GP, McLean AS, Booth DR, Armstrong NJ, Nalos M, Huang SJ, Manak J, Tang W, Tam OY, Chan S, Tang BM. A distinct influenza infection signature in the blood transcriptome of patients who presented with severe community acquired pneumonia. Critical Care, 2012 16(4) R157.
  • Kirschner MB, Cheng YY, Badrian B, Kao SC, Creaney J, Edelman JJ, Armstrong NJ, Vallely MP, Musk AW, Robinson BWS, McCaughan BC, Klebe S, Mutsaers SE, van Zandwijk N, Reid G. Increased circulating miR-625-3p: a potential biomarker for patients with malignant pleural mesothelioma. J Thorac Oncol, 2012 7(7):1184-91.
  • Birzniece V, Meinhardt UJ, Gibney J, Johannsson G, Armstrong N, Baxter RC, Ho KKY. Differential effects of raloxifene and estrogen on body composition in growth hormone-replaced hypopituitary women. JCEM, 2012 97(3):1005-12.
  • Kao SC, Armstrong N, Condon B, Griggs K, McCaughan B, Shepard S, Wilson A, Henderson DW, Klebe S. Aquaporin 1 is an independent prognostic factor in pleural malignant mesothelioma. Cancer, 2011 118(11):2952-2961.
  • Kirschner MB, Kao SC, Edelman JJ, Armstrong NJ, Vallely MP, van Zandwijk N, Reid G. Haemolysis during sample preparation alters microRNA content of plasma. PLoS ONE, 2011 6(9):e24125.
  • Suppiah V, Gaudieri S, Armstrong NJ, O’Connor KS, Berg T, Weltman M, Abate ML, Spengler U, Bassendine M, Dore GJ, Irving WL, Powell E, Hellard M, Riordan S, Mathews G, Sheridan D, Nattermann J, Smedile A, Muller T, Hammond E, Dunn D, Negro F, Bochud P-Y, Mallal S, Ahlenstiel G, Stewart GJ, George J, Booth DR, International Hepatitis C Genetics Consortium (IHCGC). IL28B, HLA-C and KIR variants additively and interactively predict response to therapy in chronic hepatitis C virus infection. PLoS Medicine, 2011 8(9):e1001092.
  • Kao SC, Klebe S, Henderson DW, Reid G, Chatfield M, Armstrong NJ, Yan T, Vardy J, Clarke S, van Zandwijk N, McCaughan B. Low Calretinin expression and high Neutrophil-to-Lymphocyte Ratio are poor prognostic factors in malignant mesothelioma patients undergoing extrapleural pneumonectomy. J Thorac Oncol, 2011 6(11):1923-1929.
  • Kao SC, Griggs K, Lee K, Armstrong N, Clarke S, Vardy J, van Zandwijk N, Burn J, McCaughan BC, Henderson DW, Klebe S. Validation of the use of a minimal panel of antibodies for the diagnosis of malignant pleural mesothelioma. Pathology, 2011 43(4):313-317.
  • Kao SC, Lee K, Armstrong N, Clarke S, Vardy J, van Zandwijk N, Reid G, Burn J, McCaughan BC, Henderson DW, Klebe S. Validation of tissue microarray technology in malignant pleural mesothelioma. Pathology, 2011 43(2):128-132.
  • Ghandi KS, McKay FC, Cox M, Riveros C, Armstrong N, Heard RN, Vucic S, Williams DW, Stankovich J, Brown M, Danoy P, Stewart GJ, Broadley S, Moscato P, Lechner-Scott J, Scott RJ, Booth DR, ANZgene Multiple Sclerosis Genetics Consortium. The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. Hum Mol Genet, 2010 19(11): 2134-2143.
  • Gerlach C, van Heijst JWJ, Swart E, Sie D, Armstrong N, Kerkhoven RM, Zehn D, Bevan MJ, Schepers K, Schumacher TWM. One naive T cell, multiple fates in CD8+ T cell differentiation. J Exp Medicine, 2010 207(6):1235-1246.
  • Mook S, Schmidt MK, Rutgers EJ, van de Velde AO, Visser O, Rutgers SM, Armstrong N, van ‘t Veer LJ, Ravdin PM. Calibration and discriminatory accuracy of the web-based tool Adjuvant! in a hospital-based cohort of 5380 Dutch breast cancer patients. Lancet Oncology, 2009 10(11):1070-1076.
  • Kreike B, Halfwerk H, Armstrong N, Bult P, Foekens JA, Veltkamp SC, Nuyten D, Bartelink H, van de Vijver MJ. Local recurrence after breast-conserving therapy in relation to gene expression patterns in a large series of patients. Clinical Cancer Research, 2009 15(12):4181-4190.
  • Kok M, Koornstra RH, Margarido TC, Fles R, Armstrong N, Linn SC, van ‘t Veer LJ, Weigelt B. Mammosphere-derived gene set predicts outcome in patients with ER-positive breast cancer. Journal of Pathology, 2009 218(3):316-326.
  • van den Broek GB, Wildeman M, Rasch CRN, Armstrong N, Schuuring E, Begg AC, Looijenga LHJ, Scheper R, van der Wal JE, Menkema L, van Diest PJ, Balm AJM, van Velthuysen MLF, van den Brekel MWM. Molecular markers predict outcome in squamous cell carcinoma of the head and neck after concomitant cisplatin-based chemoradiation. International Journal of Cancer, 2009 124(11):2643-2650.
  • Reyal F, van Vliet MH, Armstrong NJ, Horlings HM, de Visser KE, Kok M, Teschendorff AE, Mook S, van’t Veer L, Caldas C, Salmon RJ, van de Vijver MJ, Wessels LFA. A comprehensive analysis of prognostic signatures reveals the high predictive capacity of Proliferation, Immune response and RNA splicing modules in breast cancer. Breast Cancer Research, 2008 10(6): R93.
  • Armstrong NJ. The changing focus of microarray analysis. Statistica Neerlandica, 2008 62(3):364-373.
  • Stam FJ, Macgillavry HD, Armstrong NJ, de Gunst MC, Zhang Y, van Kesteren RE, Smit AB, Verhaagen J. Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury. European Journal of Neuroscience, 2007 25(12):3629-3637.
  • Armstrong NJ, Brodnicki TC, Speed TP. Mind the gap: analysis of marker-assisted breeding strategies for inbred mouse strains. Mammalian Genome, 2006 17(4):273-87.
  • Armstrong NJ, McPeek MS, Speed TP. Incorporating interference into linkage analysis for experimental crosses. Biostatistics, 2006 7(3):374-86.
  • Rabbee N, Speca D, Armstrong NJ, Speed TP. Power calculations for selective genotyping in QTL mapping in backcross mice. Genetics Research, 2004 84(2):103-8.
  • Armstrong NJ, van de Wiel MA. Microarray data analysis: from hypothesis to conclusions using gene expression data. Cellular Oncology, 2004 26(5-6):279-90.